1-Oxa-8-azaspiro[4.5]decane-8-carboxylic acid, 3-oxo-, 1,1-diMethylethyl ester
3-Oxo-1-oxa-8-aza-spiro[4.5]decane-8-carboxylic acid tert-butyl ester
CAS: 954236-44-3
Molecular Formula: C13H21NO4
1-Oxa-8-azaspiro[4.5]decane-8-carboxylic acid, 3-oxo-, 1,1-diMethylethyl ester - Names and Identifiers
1-Oxa-8-azaspiro[4.5]decane-8-carboxylic acid, 3-oxo-, 1,1-diMethylethyl ester - Physico-chemical Properties
| Molecular Formula | C13H21NO4 |
| Molar Mass | 255.31 |
| Density | 1.16 |
| Melting Point | 65-66 °C(Solv: hexane (110-54-3)) |
| Boling Point | 375.5±42.0 °C(Predicted) |
| pKa | -0.85±0.20(Predicted) |
| Storage Condition | 2-8°C |
1-Oxa-8-azaspiro[4.5]decane-8-carboxylic acid, 3-oxo-, 1,1-diMethylethyl ester - Introduction
3-Oxo-1-oxa-8-aza-spiro[4.5]decane-8-carboxylic acid tert-butyl ester is an organic compound with the chemical formula C14H25NO4. It is a kind of Spiro compound with special structure, which has a wide range of applications in chemical synthesis.
The compound is a white to yellow crystalline solid, soluble in common organic solvents such as dimethylformamide and dichloromethane. It is a stable compound and does not decompose easily.
3-Oxo-1-oxa-8-aza-spiro[4.5]decane-8-carboxylic acid tert-butyl ester is widely used as an intermediate in organic synthesis. It can be reacted by deprotection (removal of the Boc Group) to give its corresponding spirocyclic acid, or by reduction to give the corresponding spirocyclic alcohol. These intermediates can be further used in the synthesis of other organic compounds, such as drug synthesis, natural product synthesis, etc.
The method for preparing 3-Oxo-1-oxa-8-aza-spiro[4.5]decane-8-carboxylic acid tert-butyl ester is relatively complicated and generally involves a multi-step reaction. A common method is by reacting the corresponding morphine compound with a quaternary ammonium salt, followed by an oxylation reaction, and finally the introduction of a Boc protecting group.
regarding safety, 3-Oxo-1-oxa-8-aza-spiro[4.5]decane-8-carboxylic acid tert-butyl ester has no obvious risk when used under normal laboratory conditions. However, as chemicals, the handling and storage should strictly comply with the relevant safety regulations. When used, it is necessary to wear appropriate protective equipment and operate in a well-ventilated area. If you have any questions or unexpected situations, please ask the relevant professionals for help.
The compound is a white to yellow crystalline solid, soluble in common organic solvents such as dimethylformamide and dichloromethane. It is a stable compound and does not decompose easily.
3-Oxo-1-oxa-8-aza-spiro[4.5]decane-8-carboxylic acid tert-butyl ester is widely used as an intermediate in organic synthesis. It can be reacted by deprotection (removal of the Boc Group) to give its corresponding spirocyclic acid, or by reduction to give the corresponding spirocyclic alcohol. These intermediates can be further used in the synthesis of other organic compounds, such as drug synthesis, natural product synthesis, etc.
The method for preparing 3-Oxo-1-oxa-8-aza-spiro[4.5]decane-8-carboxylic acid tert-butyl ester is relatively complicated and generally involves a multi-step reaction. A common method is by reacting the corresponding morphine compound with a quaternary ammonium salt, followed by an oxylation reaction, and finally the introduction of a Boc protecting group.
regarding safety, 3-Oxo-1-oxa-8-aza-spiro[4.5]decane-8-carboxylic acid tert-butyl ester has no obvious risk when used under normal laboratory conditions. However, as chemicals, the handling and storage should strictly comply with the relevant safety regulations. When used, it is necessary to wear appropriate protective equipment and operate in a well-ventilated area. If you have any questions or unexpected situations, please ask the relevant professionals for help.
Last Update：2024-04-09 21:54:55
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Product Name: 3-Oxo-1-oxa-8-aza-spiro[4.5]decane-8-carboxylic acid tert-butyl ester Visit Supplier Webpage Request for quotation
CAS: 954236-44-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 954236-44-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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